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Table 1 Baseline features of the study cohort and the results of univariable logistic regression analysis

From: Associations of single nucleotide polymorphisms with mucinous colorectal cancer: genome-wide common variant and gene-based rare variant analyses

   Mucinous Non-mucinous   
Characteristics No. (%) No. (%) OR (95% CI) p-value
Agea ≤60 20 (9) 203 (91)   
60–65 17 (18) 78 (82) 2.21 (1.09–4.44) 0.025
>65 20 (11) 167 (89) 1.22 (0.63–2.34) 0.558
Sex Female 29 (15) 169 (85)   
Male 28 (9) 279 (91) 0.58 (0.34–1.02) 0.057
Location Colon 47 (14) 287 (86)   
Rectum 10 (6) 161 (94) 0.38 (0.18–0.74) 0.007
Stage I 3 (3) 90 (97)   
II 27 (14) 169 (86) 4.79 (1.64–20.45) 0.012
III 19 (11) 147 (89) 3.88 (1.28–16.83) 0.033
IV 8 (16) 42 (84) 5.71 (1.57–27.09) 0.013
Grade Well/moderately diff. 48 (10) 416 (90)   
Poorly diff. 7 (19) 30 (81) 2.02 (0.78–4.62) 0.115
Unknown 2 2   
MSI status MSI-low/MSS 49 (11) 382 (89)   
MSI-high 6 (11) 47 (89) 1.00 (0.37–2.29) 0.992
Unknown 3 18   
Lymphatic invasion Absent 31 (10) 267 (90)   
Present 23 (14) 144 (86) 1.38 (0.77–2.44) 0.278
Unknown 3 37   
BRAF V600E mutation Absent 45 (11) 366 (89)   
Present 9 (19) 38 (81) 1.93 (0.83–4.09) 0.104
Unknown 3 44   
  1. aThe age at diagnosis was separated into 3 groups: ≤60, 60–65, and > 65 since the odds ratio does not remain constant for each year increase in age at diagnosis under the logistic regression model and this particular grouping gave the most efficient odds ratio estimates with no significant change in the results when considering slightly different groupings. CI confidence interval, diff. Differentiated, MSI microsatellite instability, MSS microsatellite stable, No number, OR odds ratio (compares the odds of having mucinous tumors with the corresponding factor level to the odds of having mucinous tumors with the reference factor level)