Table 1 Baseline features of the study cohort and the results of univariable logistic regression analysis

Age^a

≤60

20 (9)

203 (91)

60–65

17 (18)

78 (82)

2.21 (1.09–4.44)

0.025

>65

20 (11)

167 (89)

1.22 (0.63–2.34)

0.558

Sex

Female

29 (15)

169 (85)

Male

28 (9)

279 (91)

0.58 (0.34–1.02)

0.057

Location

Colon

47 (14)

287 (86)

Rectum

10 (6)

161 (94)

0.38 (0.18–0.74)

0.007

Stage

I

3 (3)

90 (97)

II

27 (14)

169 (86)

4.79 (1.64–20.45)

0.012

III

19 (11)

147 (89)

3.88 (1.28–16.83)

0.033

IV

8 (16)

42 (84)

5.71 (1.57–27.09)

0.013

Grade

Well/moderately diff.

48 (10)

416 (90)

Poorly diff.

7 (19)

30 (81)

2.02 (0.78–4.62)

0.115

Unknown

2

2

MSI status

MSI-low/MSS

49 (11)

382 (89)

MSI-high

6 (11)

47 (89)

1.00 (0.37–2.29)

0.992

Unknown

3

18

Lymphatic

invasion

Absent

31 (10)

267 (90)

Present

23 (14)

144 (86)

1.38 (0.77–2.44)

0.278

Unknown

3

37

BRAF V600E

mutation

Absent

45 (11)

366 (89)

Present

9 (19)

38 (81)

1.93 (0.83–4.09)

0.104

Unknown

3

44