Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: a case control study

Table 3 Univariate tests for group mean/median differences between ASD and NEU cohorts

Measurement	Statistical test	Mean/Median values [95% CI]		p-value	C-statistic
		ASD	NEU
AA	Welch’s test	20.05 [17.04, 22.76]	20.16 [18.12, 22.03]	0.68	0.51
DGLA	Student’s t-test	2.045 [1.39, 2.80]	2.226 [1.548, 3.110]	0.03	0.62
DHA	Mann-Whitney U test	3.707 [2.05, 7.11]	3.816 [2.721, 5.347]	1.00	0.50
EPA	Mann-Whitney U test	0.349 [0.158, 0.828]	0.344 [0.225, 0.569]	1.00	0.51
Elaidic acid	Mann-Whitney U test	0.177 [0.136, 0.274]	0.176 [0.120, 0.253]	0.37	0.55
Linoleic acid	Welch’s test	14.18 [11.17, 17.26]	14.00 [12.43. 15.61]	0.45	0.53
Oleic acid	Mann-Whitney U test	13.90 [12.36, 16.31]	13.94 [11.86, 15.55]	0.94	0.52
Palmitelaidic acid	Student’s t-test	0.0198 [0.0110, 0.0286]	0.0201 [0.0105, 0.0282]	0.76	0.52
Palmitic acid	Mann-Whitney U test	25.50 [24.14, 26.87]	25.44 [24.04, 27.15]	0.93	0.50
Palmitoleic acid	Mann-Whitney U test	0.229 [0.124, 0.389]	0.205 [0.0147, 0.306]	0.30	0.56
Stearic acid	Welch’s test^a	19.27 [18.23, 20.41]	19.51 [18.24, 20.49]	0.06	0.62
DHA/AA	Mann-Whitney U test	0.190 [0.116, 0.350]	0.182 [0.140, 0.280]	0.91	0.51
EPA/AA	Mann-Whitney U test	0.0165 [0.0073, 0.0462]	0.0168 [0.0110, 0.0292]	0.95	0.51
n-3/n-6	Mann-Whitney U test	0.111 [0.0707, 0.224]	0.113 [0.0850, 0.163]	0.94	0.50
Total PUFA	Student’s t-test	26.54 [23.35, 29.90]	26.65 [24.34, 29.11]	0.69	0.52

^aindicates that Welch’s test was used after the distributions were found to not be of the same shape
Median values are provided if the Mann-Whitney U test was used for comparison; otherwise, mean values are provided. Brackets indicate 95% confidence intervals (CIs) obtained from the estimated PDFs

ISSN: 2050-7771