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Table 1 Fatty acids from erythrocyte membranes measured in this work

From: Erythrocyte fatty acid profiles in children are not predictive of autism spectrum disorder status: a case control study

Reference

Number of subjects

Age/gender matched?

Age

Abs./Rel. FA Conc.

Differences reported (ASD versus control)

 
 

ASD

Control

   

n-6

n-3

AA

DHA

EPA

AA/DHA

AA/EPA

Other

Vancassel et al. 2001 [36]

15

18a

N/N

ASD: 3-17 DD: 1-19

Relative

N.S.

↓

N.S.

↓

   

↓ n-3/n-6

Meguid et al. 2008 [37]

30

30

Y/Y

3-11

Absolute

  

↓

↓

 

↑

 

↓ linolenic and linoleic acids

Pastural et al. 2009[38]

15

11b

N/N

ASD: 8.7 ±3.9 DD: 7.9 ±2.9

Relative

  

↑

↑

↑

   

Bell et al. 2010 [15]

45

45

Y/Y

ASD: 7.5 ±3.5 DD: 7.5 ±3.6

Relative

N.S.

N.S.

N.S.

N.S.

N.S.

 

↑

↓ ALA

Bell et al. 2010 [15]

38

38a

Y/Y

ASD: 7.5 ±3.5 DD: 6.0 ±3.3

Relative

↓

N.S.

N.S.

N.S.

N.S.

 

N.S.

 

El-Ansary et al. 2011 [13]

26

26

Y/Y

ASD: 4-12 DD: 4-11

Absolute

  

↓

↓

N.S.

   

Brigandi et al. 2015 [14]

121

110

N/N

3-17

Relative

↓

↓

↓

↓

N.S.

   

Yui et al. 2016 [24]

30

20

Y/Y

ASD: 13.6 ±4.3 DD: 13.2 ±5.4

Absolute

  

↓

N.S.

↑

↓

↓

 

Jory et al. 2016 [39]

11

15

Y/N

ASD: 3.1 ±0.8 DD: 3.9 ±1.1

Relative

  

↓

↓

↓

N.S.

N.S.

↓ n-3/n-6 and linoleic acid

Parletta et al. 2016 [16]

85

79

N/Y

ASD: 5.3 ±2.1 DD: 8.3 ±2.5

Relative

  

↓

↓

↓

 

↑

↓ n-3/n-6

  1. aControl group was Developmentally Delayed instead of NEU
  2. bMany of the NEU controls were siblings of the ASD group