Skip to main content

Advertisement

Table 1 Description of the clinical material

From: Platelet protein biomarker panel for ovarian cancer diagnosis

Diagnosis and International classification of disease (ICD) coding
Benign lesions   Epithelial ovarian cancer, C56.9
n stages I-II n stages III-IV n
Serous ovarian cyst, N82.3 19 serous 2 serous 47
Ovarian fibrom, N82.3 10 mucinous 1 endometrioid 1
Dermoid ovarian cyst, N82.3 5 endometrioid 2 clear-cell 1
Endometriosis cyst, N80.1 8 clear-cell 3   
Mucinous ovarian cyst, N83.2 10     
Non-cancer ascites, R18.9 1     
Paratubar cyst, Q50.5 2     
Uterine myom, D25.9 2     
Total 57   8   49
Transvaginal sonography, IOTA classification
Ultrasound assessment Certainty in the assessment Histopathology n
Benign certainly benign   benign 7
Benign probably benign   benign 16
Benign uncertain   benign 6
Borderline tumor uncertain   benign 4
Malignant probably malignant   benign 2
Malignant certainly malignant   malignant 1a
Malignant certainly malignant   malignant 13b
no IOTA-based examination     benign 22
no IOTA-based examination     malignant 7a
no IOTA-based examination     malignant 36b
Total      114
   Medication:    
Comorbidities n coagulation/aggregation blockers n
None 99   none   111
One or few following diseases: 15   Warfarin   1
 Breast cancer remission 4   Dabigatran 1
 Cardiovascular 14   Aspirin   1
 Rheumatic 2   Total   114
 Endocrine 4   Experimental setup, n  
 Astma 2 Method/Statistics Benign Ovarian cancer, stage
 Hepatitis C 1   lesions I-II III-IV
Total 114 2D/PCA 28 8 32
  2D/PLS-DA 25 8 30
  Western blot/PLS-DA 20 8 20
  DigiWest/PLS-DA 29 0 30
  1. astages I-II
  2. bstages III-IV