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Table 1 Candidate biomarkers (measured 0–6 h after surgery)

From: Development of biomarker combinations for postoperative acute kidney injury via Bayesian model selection in a multicenter cohort study

Category Biomarker Abbreviation Source
Biomarkers of kidney injury Kidney injury molecule-1 [11] KIM-1 Urine
Liver fatty acid-binding protein [11] L-FABP Urine
Cystatin C [12]   Urine
Albumin [10, 13]   Urine
Neutrophil gelatinase-associated lipocalin [5] NGAL Urine, plasma
Interleukin-18 [5] IL-18 Urine
Biomarkers of kidney function Creatinine [5, 14] Cr Urine, seruma
Biomarkers of cardiac function Heart-type fatty acid binding protein [15] h-FABP Plasma
Brain natriuretic peptide [16] BNP Plasma
High-sensitivity troponin T [16] TNTHS Plasma
N-type pro-B-type natriuretic peptide [16] NT-proBNP Plasma
Creatine kinase-MB [16] CKMB Plasma
Troponin I [16] TNI Plasma
Biomarkers of inflammation Interleukin-6 [7] IL-6 Plasma
Interleukin-10 [7] IL-10 Plasma
Monocyte chemotactic protein-1 [17] MCP-1 Plasma
Epidermal growth factor [17] EGF Plasma
Vascular endothelial growth factor [17] VEGF Plasma
  1. aAlso considered the change from preoperative serum creatinine to 0–6 h postoperative and the average of preoperative and 0–6 h postoperative serum creatinine