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Table 2 SETBP1 mutations in juvenile myelomonocytic leukemia

From: SETBP1 mutations as a biomarker for myelodysplasia /myeloproliferative neoplasm overlap syndrome

Reference

Number of Patients

Mutation Prevalence

Impact on Survival

[46]

92

7 (7.6%)

Yes* (p-NR)

[47]

42

2 (4.8%)

NR

[48]

66

23 (24.8%)

No (p-0.258 – Univariate)

Yes (p-0.026 – Multivariate)

[49]

70

7 (10%)

Yes (p-0.03)

  1. NR Not reported; * Survival analysis was done in patients harboring SETBP1 or JAK3 mutations compared to patients without either mutation
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Biomarker Research

ISSN: 2050-7771

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