Skip to main content

Advertisement

Table 4 Correlation analysis of Discovery and SOMAScan assays

From: Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients

Cytokine r value P valuea Cytokine r value P valuea Cytokine r value P valuea
CTACK 0.0242 0.8719 IL-4 0.1467 0.3252 MCP-4 0.1200 0.4218
EGF 0.2815 0.0553 IL-5 0.1427 0.3387 MDC 0.5461 <0.0001
ENA-78 0.2833 0.0536 IL-6 0.2487 0.0918 MIP-1α −0.0028 0.9852
Eotaxin-1 0.2312 0.1179 IL-7 −0.0071 0.9618 PDGF-AA 0.7951 <0.0001
Eotaxin-2 0.1752 0.2388 IL-8 0.4526 0.0014 PDGF-BB 0.6449 <0.0001
Eotaxin-3 0.5295 0.0001 IL-9 0.1587 0.2866 RANTES −0.0445 0.7664
Flt-3 Ligand 0.4585 0.0012 IL-10 −0.2023 0.1727 sCD40L 0.4882 0.0005
Fractalkine −0.4095 0.0043 IL-13 0.0454 0.7619 SDF-1 0.2765 0.0599
G-CSF 0.0897 0.5486 IL-16 −0.2042 0.1686 TARC 0.8669 <0.0001
GM-CSF 0.1330 0.3727 IL-17A 0.1628 0.2743 TNFα 0.3373 0.0204
GROpan 0.4460 0.0017 IL-20 −0.3942 0.0061 TNFβ 0.3215 0.0275
IFNγ −0.0659 0.6595 IL-23 −0.1467 0.3252 TPO 0.1433 0.3366
IL-1A −0.0624 0.6767 IP-10 0.5764 <0.0001 TSLP −0.0460 0.7587
IL-1B 0.1263 0.3975 I-309 −0.1289 0.3877 VEGF −0.1383 0.3539
IL-1RA 0.0253 0.8661 MCP-1 0.0614 0.6818 6CKine 0.1104 0.4602
IL-2 −0.467 0.0009 MCP-2 −0.2492 0.0912    
IL-3 0.1065 0.4761 MCP-3 −0.2023 0.1728    
  1. aSpearman’s rank correlation coefficient test. Only 12 (shown in bold) of the 49 common proteins showed significant positive correlation between the Discovery and SOMAScan assays (p < 0.05)