TY - JOUR AU - Lim, Su Yin AU - Lee, Jenny H. AU - Welsh, Sarah J. AU - Ahn, Seong Beom AU - Breen, Edmond AU - Khan, Alamgir AU - Carlino, Matteo S. AU - Menzies, Alexander M. AU - Kefford, Richard F. AU - Scolyer, Richard A. AU - Long, Georgina V. AU - Rizos, Helen PY - 2017 DA - 2017/11/10 TI - Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients JO - Biomarker Research SP - 32 VL - 5 IS - 1 AB - Selective kinase and immune checkpoint inhibitors, and their combinations, have significantly improved the survival of patients with advanced metastatic melanoma. Not all patients will respond to treatment however, and some patients will present with significant toxicities. Hence, the identification of biomarkers is critical for the selection and management of patients receiving treatment. Biomarker discovery often involves proteomic techniques that simultaneously profile multiple proteins but few studies have compared these platforms. SN - 2050-7771 UR - https://doi.org/10.1186/s40364-017-0112-9 DO - 10.1186/s40364-017-0112-9 ID - Lim2017 ER -