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Fig. 1 | Biomarker Research

Fig. 1

From: “UPRegulation” of CD47 by the endoplasmic reticulum stress pathway controls anti-tumor immune responses

Fig. 1

Co-expression of GRP78 and CD47 is associated with poor prognosis in breast cancer. Kaplan-Meier curves indicating relapse-free survival (RFS) of breast cancer patients were obtained by using KM plotter (2017 version for breast cancer) [10]. Effects of co-expression of GRP78 and CD47 on RFS are shown for (a) breast cancer patients regardless of hormone receptor and HER2- tumor status; (b) ER+, PR+, and HER2-negative breast cancer; (c) ER+ patients with ER+ tumors who endocrine targeted therapies; and (d) patients with ER- tumors. e, f Data mining of breast cancer cases using the METABRIC database (

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