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Table 5 Differences of miRNA

From: Tissue MicroRNA profiles as diagnostic and prognostic biomarkers in patients with resectable pancreatic ductal adenocarcinoma and periampullary cancers

Unadjusted effects on differences Adjusted effects on differences
miRNA1 miRNA2 HR (CI) P N miRNA1 miRNA2 HR (CI) P N
PDAC + AAC
miR-148a miR-212-3p 1.20 (1.09–1.33) 0.0002 155 miR-34a-5p miR-148a 0.82 (0.73–0.92) 0.0011 144
miR-205-5p miR-769-5p 0.90 (0.85–0.95) 0.0003 129 miR-205-5p miR-769-5p 0.91 (0.85–0.96) 0.0015 119
miR-148a miR-205-5p 1.08 (1.04–1.13) 0.0004 130 miR-146a-5p miR-212-3p 1.33 (1.11–1.60) 0.0017 145
miR-34a-5p miR-148a 0.83 (0.75–0.92) 0.0009 155 miR-34a-5p miR-187 0.67 (0.52–0.88) 0.0038 44
miR-34a-5p miR-187 0.64 (0.50–0.83) 0.0009 47 miR-148a miR-205-5p 1.07 (1.02–1.12) 0.004 120
miR-146a-5p miR-212-3p 1.32 (1.12–1.57) 0.0013 156 miR-29a-5p miR-205-5p 1.08 (1.03–1.15) 0.0046 119
miR-187 miR-212-3p 1.55 (1.18–2.04) 0.0016 47 miR-125a-3p miR-769-5p 0.81 (0.69–0.94) 0.0071 140
miR-34a-5p miR-769-5p 0.74 (0.62–0.89) 0.0017 154 miR-187 miR-212-3p 1.47 (1.11–1.96) 0.0078 44
miR-212-3p miR-769-5p 0.81 (0.70–0.92) 0.0020 154 let-7 g miR-187 0.74 (0.59–0.93) 0.0085 44
miR-205-5p miR-625-5p 0.91 (0.86–0.97) 0.0023 72 miR-146a-5p miR-205-5p 1.08 (1.02–1.14) 0.0097 120
miR-205-5p miR-450b-5p 0.91 (0.86–0.97) 0.0031 94 miR-205-5p miR-222-5p 0.93 (0.87–0.99) 0.0152 117
miR-146a-5p miR-205-5p 1.08 (1.03–1.14) 0.0033 130 miR-29a-5p miR-769-5p 0.81 (0.68–0.96) 0.0171 143
miR-205-5p miR-222-5p 0.92 (0.86–0.97) 0.0034 127 let-7 g miR-205-5p 1.07 (1.01–1.13) 0.018 120
let-7 g miR-205-5p 1.08 (1.02–1.14) 0.0048 130 miR-29a-5p miR-194-3p 0.68 (0.50–0.94) 0.0188 46
miR-194-3p miR-205-5p 1.26 (1.07–1.48) 0.0062 36 miR-125a-3p miR-187 0.76 (0.61–0.96) 0.0188 43
miR-29a-5p miR-205-5p 1.07 (1.02–1.13) 0.0072 129 let-7 g miR-212-3p 1.14 (1.02–1.28) 0.0233 144
miR-125a-3p miR-205-5p 1.08 (1.02–1.15) 0.0074 128 miR-125a-3p miR-205-5p 1.07 (1.01–1.14) 0.0236 118
let-7 g miR-187 0.82 (0.70–0.95) 0.0093 47 miR-205-5p miR-450b-5p 0.93 (0.87–0.99) 0.024 85
miR-34a-5p miR-205-5p 1.07 (1.02–1.13) 0.0125 130 miR-34a-5p miR-194-3p 0.64 (0.43–0.94) 0.0262 45
miR-125a-3p miR-148a 0.90 (0.83–0.98) 0.0139 152 miR-194-3p miR-212-3p 1.39 (1.04–1.85) 0.0273 45
miR-125a-3p miR-769-5p 0.84 (0.73–0.97) 0.0146 151 miR-212-3p miR-625-5p 0.86 (0.75–0.98) 0.0298 74
miR-125a-3p miR-187 0.80 (0.66–0.96) 0.0155 46 miR-34a-5p miR-205-5p 1.07 (1.01–1.13) 0.0307 120
miR-212-3p miR-625-5p 0.87 (0.77–0.98) 0.0194 79 miR-194-3p miR-205-5p 1.21 (1.02–1.45) 0.0326 33
let-7 g miR-212-3p 1.12 (1.01–1.25) 0.0332 155 miR-625-5p miR-944 1.51 (1.03–2.22) 0.0339 20
miR-187 miR-194-3p 1.41 (1.02–1.96) 0.0366 21 miR-125a-3p miR-148a 0.91 (0.84–1.00) 0.0383 141
miR-205-5p miR-212-3p 0.95 (0.90–1.00) 0.0410 130 miR-146a-5p miR-769-5p 0.84 (0.71–1.00) 0.0394 144
miR-34a-5p miR-625-5p 0.88 (0.78–1.00) 0.0443 79 miR-34a-5p miR-625-5p 0.87 (0.75–1.00) 0.0478 74
miR-146a-5p miR-187 0.79 (0.63–1.00) 0.0452 47      
miR-187 miR-205-5p 1.12 (1.00–1.26) 0.0468 38      
miR-34a-5p miR-146a-5p 0.83 (0.68–1.00) 0.0488 156      
PDAC  
miR-148a miR-212-3p 1.18 (1.04–1.33) 0.0077 103 miR-34a-5p miR-769-5p 0.63 (0.47–0.84) 0.002 92
miR-34a-5p miR-148a 0.86 (0.76–0.97) 0.0156 103 miR-29a-5p miR-187 1.99 (1.20–3.29) 0.0072 20
miR-34a-5p miR-769-5p 0.75 (0.59–0.96) 0.0199 102 miR-187 miR-769-5p 0.54 (0.33–0.87) 0.0111 20
miR-146a-5p miR-212-3p 1.26 (1.01–1.56) 0.0371 103 miR-187 miR-205-5p 0.72 (0.56–0.94) 0.0138 19
miR-34a-5p miR-146a-5p 0.74 (0.56–0.99) 0.0427 103 miR-212-3p miR-769-5p 0.75 (0.60–0.95) 0.0153 92
      miR-148a miR-212-3p 1.18 (1.03–1.34) 0.016 93
      miR-450b-5p miR-944 1.56 (1.06–2.30) 0.0243 24
      miR-34a-5p miR-148a 0.86 (0.75–0.99) 0.0341 93
      miR-146a-5p miR-212-3p 1.29 (1.02–1.63) 0.0343 93
      miR-148a miR-431-5p 1.32 (1.02–1.72) 0.0364 34
      miR-146a-5p miR-187 1.57 (1.01–2.44) 0.0438 20
      miR-222-5p miR-769-5p 0.84 (0.70–1.00) 0.0491 92
A-AC  
miR-205-5p miR-769-5p 0.71 (0.60–0.84) <0.0001 36 miR-34a-5p miR-769-5p 0.51 (0.32–0.81) 0.0043 51
miR-34a-5p miR-187 0.44 (0.27–0.72) 0.0011 24 miR-125a-3p miR-187 0.37 (0.18–0.75) 0.0055 23
miR-148a miR-205-5p 1.25 (1.09–1.44) 0.0018 37 miR-34a-5p miR-187 0.48 (0.28–0.82) 0.0067 24
miR-125a-3p miR-187 0.69 (0.54–0.88) 0.0032 23 miR-148a miR-187 0.59 (0.40–0.87) 0.0074 24
miR-187 miR-205-5p 1.35 (1.10–1.66) 0.0041 17 miR-29a-5p miR-769-5p 0.65 (0.48–0.89) 0.0077 52
miR-187 miR-212-3p 2.22 (1.29–3.82) 0.0042 24 miR-222-5p miR-450b-5p 2.12 (1.18–3.81) 0.0123 25
miR-205-5p miR-450b-5p 0.73 (0.59–0.91) 0.0045 22 miR-187 miR-769-5p 2.09 (1.16–3.78) 0.0148 24
let-7 g miR-205-5p 1.28 (1.07–1.52) 0.006 37 miR-29a-5p miR-187 0.62 (0.42–0.91) 0.0154 24
miR-146a-5p miR-205-5p 1.19 (1.05–1.34) 0.0065 37 miR-187 miR-212-3p 2.23 (1.16–4.30) 0.016 24
let-7 g miR-769-5p 0.74 (0.59–0.93) 0.0083 52 miR-146a-5p miR-187 0.54 (0.33–0.90) 0.0175 24
miR-34a-5p miR-769-5p 0.66 (0.48–0.91) 0.0122 52 miR-148a miR-450b-5p 2.12 (1.14–3.96) 0.0181 26
miR-34a-5p miR-205-5p 1.22 (1.04–1.43) 0.0126 37 miR-450b-5p miR-769-5p 0.31 (0.12–0.84) 0.0214 26
let-7 g miR-187 0.77 (0.62–0.95) 0.017 24 miR-34a-5p miR-625-5p 0.71 (0.52–0.96) 0.0267 30
let-7 g miR-625-5p 0.74 (0.58–0.95) 0.0175 31 miR-125a-3p miR-769-5p 0.75 (0.58–0.97) 0.0283 49
miR-125a-3p miR-205-5p 1.21 (1.03–1.43) 0.0227 36 miR-29a-5p miR-625-5p 0.74 (0.56–0.99) 0.0408 30
let-7 g miR-222-5p 0.80 (0.67–0.97) 0.0242 50 miR-205-5p miR-222-5p 0.81 (0.66–0.99) 0.0436 33
miR-29a-5p miR-187 0.74 (0.56–0.97) 0.0272 24      
miR-205-5p miR-212-3p 0.86 (0.75–0.98) 0.0289 37      
miR-146a-5p miR-187 0.67 (0.46–0.96) 0.0308 24      
miR-187 miR-769-5p 1.47 (1.02–2.11) 0.0367 24      
miR-450b-5p miR-769-5p 0.59 (0.35–1.00) 0.0489 27