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Table 5 Differences of miRNA

From: Tissue MicroRNA profiles as diagnostic and prognostic biomarkers in patients with resectable pancreatic ductal adenocarcinoma and periampullary cancers

Unadjusted effects on differences

Adjusted effects on differences

miRNA1

miRNA2

HR (CI)

P

N

miRNA1

miRNA2

HR (CI)

P

N

PDAC + AAC

miR-148a

miR-212-3p

1.20 (1.09–1.33)

0.0002

155

miR-34a-5p

miR-148a

0.82 (0.73–0.92)

0.0011

144

miR-205-5p

miR-769-5p

0.90 (0.85–0.95)

0.0003

129

miR-205-5p

miR-769-5p

0.91 (0.85–0.96)

0.0015

119

miR-148a

miR-205-5p

1.08 (1.04–1.13)

0.0004

130

miR-146a-5p

miR-212-3p

1.33 (1.11–1.60)

0.0017

145

miR-34a-5p

miR-148a

0.83 (0.75–0.92)

0.0009

155

miR-34a-5p

miR-187

0.67 (0.52–0.88)

0.0038

44

miR-34a-5p

miR-187

0.64 (0.50–0.83)

0.0009

47

miR-148a

miR-205-5p

1.07 (1.02–1.12)

0.004

120

miR-146a-5p

miR-212-3p

1.32 (1.12–1.57)

0.0013

156

miR-29a-5p

miR-205-5p

1.08 (1.03–1.15)

0.0046

119

miR-187

miR-212-3p

1.55 (1.18–2.04)

0.0016

47

miR-125a-3p

miR-769-5p

0.81 (0.69–0.94)

0.0071

140

miR-34a-5p

miR-769-5p

0.74 (0.62–0.89)

0.0017

154

miR-187

miR-212-3p

1.47 (1.11–1.96)

0.0078

44

miR-212-3p

miR-769-5p

0.81 (0.70–0.92)

0.0020

154

let-7 g

miR-187

0.74 (0.59–0.93)

0.0085

44

miR-205-5p

miR-625-5p

0.91 (0.86–0.97)

0.0023

72

miR-146a-5p

miR-205-5p

1.08 (1.02–1.14)

0.0097

120

miR-205-5p

miR-450b-5p

0.91 (0.86–0.97)

0.0031

94

miR-205-5p

miR-222-5p

0.93 (0.87–0.99)

0.0152

117

miR-146a-5p

miR-205-5p

1.08 (1.03–1.14)

0.0033

130

miR-29a-5p

miR-769-5p

0.81 (0.68–0.96)

0.0171

143

miR-205-5p

miR-222-5p

0.92 (0.86–0.97)

0.0034

127

let-7 g

miR-205-5p

1.07 (1.01–1.13)

0.018

120

let-7 g

miR-205-5p

1.08 (1.02–1.14)

0.0048

130

miR-29a-5p

miR-194-3p

0.68 (0.50–0.94)

0.0188

46

miR-194-3p

miR-205-5p

1.26 (1.07–1.48)

0.0062

36

miR-125a-3p

miR-187

0.76 (0.61–0.96)

0.0188

43

miR-29a-5p

miR-205-5p

1.07 (1.02–1.13)

0.0072

129

let-7 g

miR-212-3p

1.14 (1.02–1.28)

0.0233

144

miR-125a-3p

miR-205-5p

1.08 (1.02–1.15)

0.0074

128

miR-125a-3p

miR-205-5p

1.07 (1.01–1.14)

0.0236

118

let-7 g

miR-187

0.82 (0.70–0.95)

0.0093

47

miR-205-5p

miR-450b-5p

0.93 (0.87–0.99)

0.024

85

miR-34a-5p

miR-205-5p

1.07 (1.02–1.13)

0.0125

130

miR-34a-5p

miR-194-3p

0.64 (0.43–0.94)

0.0262

45

miR-125a-3p

miR-148a

0.90 (0.83–0.98)

0.0139

152

miR-194-3p

miR-212-3p

1.39 (1.04–1.85)

0.0273

45

miR-125a-3p

miR-769-5p

0.84 (0.73–0.97)

0.0146

151

miR-212-3p

miR-625-5p

0.86 (0.75–0.98)

0.0298

74

miR-125a-3p

miR-187

0.80 (0.66–0.96)

0.0155

46

miR-34a-5p

miR-205-5p

1.07 (1.01–1.13)

0.0307

120

miR-212-3p

miR-625-5p

0.87 (0.77–0.98)

0.0194

79

miR-194-3p

miR-205-5p

1.21 (1.02–1.45)

0.0326

33

let-7 g

miR-212-3p

1.12 (1.01–1.25)

0.0332

155

miR-625-5p

miR-944

1.51 (1.03–2.22)

0.0339

20

miR-187

miR-194-3p

1.41 (1.02–1.96)

0.0366

21

miR-125a-3p

miR-148a

0.91 (0.84–1.00)

0.0383

141

miR-205-5p

miR-212-3p

0.95 (0.90–1.00)

0.0410

130

miR-146a-5p

miR-769-5p

0.84 (0.71–1.00)

0.0394

144

miR-34a-5p

miR-625-5p

0.88 (0.78–1.00)

0.0443

79

miR-34a-5p

miR-625-5p

0.87 (0.75–1.00)

0.0478

74

miR-146a-5p

miR-187

0.79 (0.63–1.00)

0.0452

47

     

miR-187

miR-205-5p

1.12 (1.00–1.26)

0.0468

38

     

miR-34a-5p

miR-146a-5p

0.83 (0.68–1.00)

0.0488

156

     

PDAC

 

miR-148a

miR-212-3p

1.18 (1.04–1.33)

0.0077

103

miR-34a-5p

miR-769-5p

0.63 (0.47–0.84)

0.002

92

miR-34a-5p

miR-148a

0.86 (0.76–0.97)

0.0156

103

miR-29a-5p

miR-187

1.99 (1.20–3.29)

0.0072

20

miR-34a-5p

miR-769-5p

0.75 (0.59–0.96)

0.0199

102

miR-187

miR-769-5p

0.54 (0.33–0.87)

0.0111

20

miR-146a-5p

miR-212-3p

1.26 (1.01–1.56)

0.0371

103

miR-187

miR-205-5p

0.72 (0.56–0.94)

0.0138

19

miR-34a-5p

miR-146a-5p

0.74 (0.56–0.99)

0.0427

103

miR-212-3p

miR-769-5p

0.75 (0.60–0.95)

0.0153

92

     

miR-148a

miR-212-3p

1.18 (1.03–1.34)

0.016

93

     

miR-450b-5p

miR-944

1.56 (1.06–2.30)

0.0243

24

     

miR-34a-5p

miR-148a

0.86 (0.75–0.99)

0.0341

93

     

miR-146a-5p

miR-212-3p

1.29 (1.02–1.63)

0.0343

93

     

miR-148a

miR-431-5p

1.32 (1.02–1.72)

0.0364

34

     

miR-146a-5p

miR-187

1.57 (1.01–2.44)

0.0438

20

     

miR-222-5p

miR-769-5p

0.84 (0.70–1.00)

0.0491

92

A-AC

 

miR-205-5p

miR-769-5p

0.71 (0.60–0.84)

<0.0001

36

miR-34a-5p

miR-769-5p

0.51 (0.32–0.81)

0.0043

51

miR-34a-5p

miR-187

0.44 (0.27–0.72)

0.0011

24

miR-125a-3p

miR-187

0.37 (0.18–0.75)

0.0055

23

miR-148a

miR-205-5p

1.25 (1.09–1.44)

0.0018

37

miR-34a-5p

miR-187

0.48 (0.28–0.82)

0.0067

24

miR-125a-3p

miR-187

0.69 (0.54–0.88)

0.0032

23

miR-148a

miR-187

0.59 (0.40–0.87)

0.0074

24

miR-187

miR-205-5p

1.35 (1.10–1.66)

0.0041

17

miR-29a-5p

miR-769-5p

0.65 (0.48–0.89)

0.0077

52

miR-187

miR-212-3p

2.22 (1.29–3.82)

0.0042

24

miR-222-5p

miR-450b-5p

2.12 (1.18–3.81)

0.0123

25

miR-205-5p

miR-450b-5p

0.73 (0.59–0.91)

0.0045

22

miR-187

miR-769-5p

2.09 (1.16–3.78)

0.0148

24

let-7 g

miR-205-5p

1.28 (1.07–1.52)

0.006

37

miR-29a-5p

miR-187

0.62 (0.42–0.91)

0.0154

24

miR-146a-5p

miR-205-5p

1.19 (1.05–1.34)

0.0065

37

miR-187

miR-212-3p

2.23 (1.16–4.30)

0.016

24

let-7 g

miR-769-5p

0.74 (0.59–0.93)

0.0083

52

miR-146a-5p

miR-187

0.54 (0.33–0.90)

0.0175

24

miR-34a-5p

miR-769-5p

0.66 (0.48–0.91)

0.0122

52

miR-148a

miR-450b-5p

2.12 (1.14–3.96)

0.0181

26

miR-34a-5p

miR-205-5p

1.22 (1.04–1.43)

0.0126

37

miR-450b-5p

miR-769-5p

0.31 (0.12–0.84)

0.0214

26

let-7 g

miR-187

0.77 (0.62–0.95)

0.017

24

miR-34a-5p

miR-625-5p

0.71 (0.52–0.96)

0.0267

30

let-7 g

miR-625-5p

0.74 (0.58–0.95)

0.0175

31

miR-125a-3p

miR-769-5p

0.75 (0.58–0.97)

0.0283

49

miR-125a-3p

miR-205-5p

1.21 (1.03–1.43)

0.0227

36

miR-29a-5p

miR-625-5p

0.74 (0.56–0.99)

0.0408

30

let-7 g

miR-222-5p

0.80 (0.67–0.97)

0.0242

50

miR-205-5p

miR-222-5p

0.81 (0.66–0.99)

0.0436

33

miR-29a-5p

miR-187

0.74 (0.56–0.97)

0.0272

24

     

miR-205-5p

miR-212-3p

0.86 (0.75–0.98)

0.0289

37

     

miR-146a-5p

miR-187

0.67 (0.46–0.96)

0.0308

24

     

miR-187

miR-769-5p

1.47 (1.02–2.11)

0.0367

24

     

miR-450b-5p

miR-769-5p

0.59 (0.35–1.00)

0.0489

27

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