Study | Index | Designed sensitivity | cutoff | Sensitivity (CI) | Specificity (CI) | Accuracy (CI) | AUC (CI) | TP | TN | FP | FN |
---|---|---|---|---|---|---|---|---|---|---|---|
Performance of diagnostic indices developed on PC vs. HS | |||||||||||
PC vs. HS | I | 0.85 | −9.13 | 84.85 (78.45–89.95) | 100.00 (90.00–100.00) | 87.50 (82.10–91.74) | 1.00 (1.00–1.00) | 140 | 35 | 0 | 25 |
A-AC vs. HS | I |  | −9.13 | 74.58 (61.56–85.02) | 100.00 (90.00–100.00) | 84.04 (75.05–90.78) | 0.99 (0.96–1.00) | 44 | 35 | 0 | 15 |
DC vs. HS | I |  | −9.13 | 100.00 (54.07–100.00) | 100.00 (90.00–100.00) | 100.00 (91.40–100.00) | 1.00 (1.00–1.00) | 6 | 35 | 0 | 0 |
CBD vs. HS | I |  | −9.13 | 66.67 (43.03–85.41) | 100.00 (90.00–100.00) | 87.50 (75.93–94.82) | 1.00 (0.99–1.00) | 14 | 35 | 0 | 7 |
A-AC, DC, CBD vs. HS | I |  | −9.13 | 74.42 (63.87–83.22) | 100.00 (90.00–100.00) | 81.82 (73.78–88.24) | 0.99 (0.97–1.00) | 64 | 35 | 0 | 22 |
GC vs. HS | I |  | −9.13 | 100.00 (83.16–100.00) | 100.00 (90.00–100.00) | 100.00 (93.51–100.00) | 1.00 (1.00–1.00) | 20 | 35 | 0 | 0 |
PC vs. HS | II | 0.85 | 16.68 | 84.85 (78.45–89.95) | 100.00 (90.00–100.00) | 87.50 (82.10–91.74) | 1.00 (1.00–1.00) | 140 | 35 | 0 | 25 |
A-AC vs. HS | II |  | 16.68 | 67.80 (54.36–79.38) | 100.00 (90.00–100.00) | 79.79 (70.25–87.37) | 0.94 (0.89–0.98) | 40 | 35 | 0 | 19 |
DC vs. HS | II |  | 16.68 | 83.33 (35.88–99.58) | 100.00 (90.00–100.00) | 97.56 (87.14–99.94) | 1.00 (1.00–1.00) | 5 | 35 | 0 | 1 |
CBD vs. HS | II |  | 16.68 | 80.95 (58.09–94.55) | 100.00 (90.00–100.00) | 92.86 (82.71–98.02) | 0.97 (0.90–1.00) | 17 | 35 | 0 | 4 |
A-AC, DC, CBD vs. HS | II |  | 16.68 | 72.09 (61.38–81.23) | 100.00 (90.00–100.00) | 80.17 (71.94–86.86) | 0.95 (0.91–0.99) | 62 | 35 | 0 | 24 |
GC vs. HS | II |  | 16.68 | 95.00 (75.13–99.87) | 100.00 (90.00–100.00) | 98.18 (90.28–99.95) | 0.96 (0.87–1.00) | 19 | 35 | 0 | 1 |
PC vs. HS | III | 0.85 | 149.10 | 84.85 (78.45–89.95) | 100.00 (90.00–100.00) | 87.50 (82.10–91.74) | 1.00 (1.00–1.00) | 140 | 35 | 0 | 25 |
A-AC vs. HS | III |  | 149.10 | 72.88 (59.73–83.64) | 100.00 (90.00–100.00) | 82.98 (73.84–89.95) | 0.98 (0.95–1.00) | 43 | 35 | 0 | 16 |
DC vs. HS | III |  | 149.10 | 66.67 (22.28–95.67) | 100.00 (90.00–100.00) | 95.12 (83.47–99.40) | 1.00 (1.00–1.00) | 4 | 35 | 0 | 2 |
CBD vs. HS | III |  | 149.10 | 71.43 (47.82–88.72) | 100.00 (90.00–100.00) | 89.29 (78.12–95.97) | 1.00 (0.99–1.00) | 15 | 35 | 0 | 6 |
A-AC, DC, CBD vs. HS | III |  | 149.10 | 72.09 (61.38–81.23) | 100.00 (90.00–100.00) | 80.17 (71.94–86.86) | 0.99 (0.97–1.00) | 62 | 35 | 0 | 24 |
GC vs. HS | III |  | 149.10 | 100.00 (83.16–100.00) | 100.00 (90.00–100.00) | 100.00 (93.51–100.00) | 1.00 (1.00–1.00) | 20 | 35 | 0 | 0 |
Performance of diagnostic indices developed on PC vs. HS + CP | |||||||||||
PC vs. HS + CP | IV | 0.85 | −9.13 | 84.85 (78.45–89.95) | 75.68 (64.31–84.90) | 82.01 (76.54–86.66) | 0.89 (0.84–0.94) | 140 | 56 | 18 | 25 |
A-AC vs. HS + CP | IV |  | −9.13 | 74.58 (61.56–85.02) | 75.68 (64.31–84.90) | 75.19 (66.96–82.26) | 0.83 (0.76–0.90) | 44 | 56 | 18 | 15 |
DC vs. HS + CP | IV |  | −9.13 | 100.00 (54.07–100.00) | 75.68 (64.31–84.90) | 77.50 (66.79–86.09) | 0.85 (0.76–0.93) | 6 | 56 | 18 | 0 |
4 vs. HS + CP | IV |  | −9.13 | 66.67 (43.03–85.41) | 75.68 (64.31–84.90) | 73.68 (63.65–82.19) | 0.80 (0.71–0.88) | 14 | 56 | 18 | 7 |
A-AC, DC, CBD vs. HS + CP | IV |  | −9.13 | 74.42 (63.87–83.22) | 75.68 (64.31–84.90) | 75.00 (67.55–81.50) | 0.83 (0.76–0.89) | 64 | 56 | 18 | 22 |
CG vs. HS + CP | IV |  | −9.13 | 100.00 (83.16–100.00) | 75.68 (64.31–84.90) | 80.85 (71.44–88.24) | 0.97 (0.93–1.00) | 20 | 56 | 18 | 0 |
PC vs. HS + CP | V | 0.85 | 1.38 | 84.85 (78.45–89.95) | 91.89 (83.18–96.97) | 87.03 (82.10–91.01) | 0.96 (0.94–0.98) | 140 | 68 | 6 | 25 |
A-AC vs. HS + CP | V |  | 1.38 | 77.97 (65.27–87.71) | 91.89 (83.18–96.97) | 85.71 (78.59–91.17) | 0.93 (0.87–0.97) | 46 | 68 | 6 | 13 |
DC vs. HS + CP | V |  | 1.38 | 100.00 (54.07–100.00) | 91.89 (83.18–96.97) | 92.50 (84.39–97.20) | 1.00 (0.98–1.00) | 6 | 68 | 6 | 0 |
CBD vs. HS + CP | V |  | 1.38 | 85.71 (63.66–96.95) | 91.89 (83.18–96.97) | 90.53 (82.78–95.58) | 0.94 (0.89–0.98) | 18 | 68 | 6 | 3 |
A-AC, DC, CBD vs. HS + CP | V |  | 1.38 | 81.40 (71.55–88.98) | 91.89 (83.18–96.97) | 86.25 (79.93–91.18) | 0.94 (0.89–0.97) | 70 | 68 | 6 | 16 |
GC vs. HS + CP | V |  | 1.38 | 95.00 (75.13–99.87) | 91.89 (83.18–96.97) | 92.55 (85.26–96.95) | 0.99 (0.96–1.00) | 19 | 68 | 6 | 1 |
PC vs. HS + CP | VI | 0.85 | 1.46 | 84.85 (78.45–89.95) | 93.24 (84.93–97.77) | 87.45 (82.57–91.37) | 0.97 (0.95–0.99) | 140 | 69 | 5 | 25 |
A-AC vs. HS + CP | VI |  | 1.46 | 72.88 (59.73–83.64) | 93.24 (84.93–97.77) | 84.21 (76.88–89.95) | 0.92 (0.87–0.96) | 43 | 69 | 5 | 16 |
DC vs. HS + CP | VI |  | 1.46 | 100.00 (54.07–100.00) | 93.24 (84.93–97.77) | 93.75 (86.01–97.94) | 0.99 (0.97–1.00) | 6 | 69 | 5 | 0 |
CBD vs. HS + CP | VI |  | 1.46 | 76.19 (52.83–91.78) | 93.24 (84.93–97.77) | 89.47 (81.49–94.84) | 0.93 (0.87–0.98) | 16 | 69 | 5 | 5 |
A-AC, DC, CBD vs. HS + CP | VI |  | 1.46 | 75.58 (65.13–84.20) | 93.24 (84.93–97.77) | 83.75 (77.10–89.10) | 0.93 (0.89–0.96) | 65 | 69 | 5 | 21 |
GC vs. HS + CP | VI |  | 1.46 | 75.00 (50.90–91.34) | 93.24 (84.93–97.77) | 89.36 (81.30–94.78) | 0.91 (0.80–0.98) | 15 | 69 | 5 | 5 |