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Table 2 Real-time RT-PCR results in groups with/without preoperative RT and with/without postoperative cervical WHDs

From: NOS1-, NOS3-, PIK3CA-, and MAPK-pathways in skin following radiation therapy

Gen

Median Expression per GAPDH

Median Expression per GAPDH

RT

No RT

 

WHD

No WHD

 

N (%)

N (%)

p Value

N (%)

N (%)

p Value

MAPK

9.32 E-01

9.65 E-03

.263

9.36 E-01

1.15 E-01

.043*

 

15 (50)

15 (50)

 

13 (43.3)

17 (56.7)

 

NOS1

6.65 E-05

5.86 E + 14

.178

7.67 E-05

5.173 E + 14

.241

 

15 (50)

15 (50)

 

13 (43.3)

17 (56.7)

 

NOS3

9.66 E-04

7.77 E-04

.089

9.86 E-04

7.84 E-04

.680

 

15 (50)

15 (50)

 

13 (43.3)

17 (56.7)

 

PIK3CA

1.99 E + 17

2.16 E + 06

.049*

6.48 E + 03

1.76 E + 17

.391

 

15 (50)

15 (50)

 

13 (43.3)

17 (56.7)

 
  1. Abbreviations: WHD wound healing disorder; RT radiation therapy; RT-PCR reverse-transcription polymerase chain reaction
  2. Data in parentheses are percentages, unless noted otherwise; *statistically significant difference at α = 0.05