From: CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia
Cell Subset | Prognosis | Reference |
---|---|---|
CD34 + | positive/negative | CD34 expression is favorable and significant prognosis in childhood B-lineage ALL (age 1 to 10Â years). [26] CD34 mostly expressed in poor risk adult B-ALLs patients, characterized with higher WBC cell count, and higher percentage of peripheral blood leukemic cells [27] |
CD38 + | positive | Ph + ALL showed lower CD38 expression than Ph- groups. Overall survival favored ALL patients with higher CD38 levels [26] |
CD34 + CD38− cells | negative | A high proportion of CD34+/CD38- cells is associated with clinical and biological features and a poor prognosis of childhood ALL. [25] |
CD10 + CD19 + CD34+ | positive | With CD10 + CD19’CD34+ immature B-progenitor subset, pediatric B-lineage ALL patients may have favorable characteristics to achieve favorable EFS outcomes. [24] |