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Table 3 Summary of the 20 pairs of miRNAs detected by differential correlation between Normal and MCI. The miRNA pairs are ranked by the difference of the correlation coefficients. The mean AUC value for the 20 miRNA pairs is 0.800 ± 0.051

From: Plasma microRNA biomarker detection for mild cognitive impairment using differential correlation analysis

Rank Pair of miRNAs |r 1r 2| log10 AUC Correlation Coefficients
     p-value   Normal (r 1) MCI (r 2)
1 hsa-miR-191 hsa-miR-590-5p 0.963 -3.76 0.880 0.764 -0.200
2 hsa-miR-125b hsa-miR-18a 0.930 -3.55 0.733 -0.218 0.712
3 hsa-miR-140-3p hsa-miR-191 0.921 -2.85 0.800 0.540 -0.381
4 hsa-miR-103 hsa-miR-19b 0.917 -3.56 0.797 0.776 -0.141
5 hsa-miR-192 hsa-miR-197 0.912 -3.61 0.867 -0.281 0.631
6 hsa-miR-191 hsa-miR-19b 0.911 -4.10 0.854 0.826 -0.085
7 hsa-miR-152 hsa-miR-191 0.892 -3.42 0.863 0.772 -0.121
8 hsa-miR-103 hsa-miR-590-5p 0.888 -3.24 0.749 0.614 -0.275
9 hsa-miR-191 hsa-miR-320a 0.873 -3.38 0.872 0.691 -0.182
10 hsa-miR-125b hsa-miR-20a 0.871 -3.80 0.801 -0.090 0.781
11 hsa-miR-106a hsa-miR-125b 0.869 -3.94 0.785 -0.083 0.786
12 hsa-miR-101 hsa-miR-103 0.865 -3.65 0.768 0.805 -0.060
13 hsa-miR-125b hsa-miR-24 0.840 -3.42 0.801 -0.073 0.768
14 hsa-miR-101 hsa-miR-191 0.831 -3.96 0.871 0.822 -0.009
15 hsa-miR-103 hsa-miR-222 0.828 -3.24 0.745 0.622 -0.207
16 hsa-miR-197 hsa-miR-378 0.820 -2.78 0.810 -0.234 0.586
17 hsa-miR-103 hsa-miR-223 0.815 -3.79 0.786 0.840 0.025
18 hsa-miR-125b hsa-miR-223 0.815 -3.49 0.765 -0.015 0.800
19 hsa-let-7b hsa-miR-125b 0.811 -3.75 0.718 -0.056 0.755
20 hsa-miR-125b hsa-miR-484 0.801 -3.52 0.739 -0.078 0.723
  1. Bold: top five miRNAs