Grade | Description | Histological features |
---|---|---|
0 | Normal | Scattered plasma cells in the lamina propria. No lymphoid follicles. |
1 | Chronic active gastritis | Small clusters of lymphocytes in the lamina propria. No lymphoid follicles. No LELs. |
2 | Chronic active gastritis with florid lymphoid follicle formation | Prominent lymphoid follicles with surrounding mantle zone and plasma cells. |
3 | Suspicious lymphoid infiltrate, probably reactive | Lymphoid follicles surrounded by CCL cells that infiltrate diffusely into the lamina propria and occasionally into the epithelium. |
4 | Suspicious lymphoid infiltrate, probably lymphoma | Lymphoid follicles surrounded by CCL cells that infiltrate diffusely into the lamina propria and into the epithelium in small groups. |
5 | Low-grade B-cell lymphoma of MALT | Presence of dense diffuse infiltrate of CCL cells in the lamina propria with prominent lymphoepithelial lesions. |