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Table 4 Serum levels of proinflammatory cytokines in two groups of patients

From: The effect of n-3 polyunsaturated fatty acids on incidence and severity of oxaliplatin induced peripheral neuropathy: a randomized controlled trial

  n-3 PUFAs (Median, percentile 25–75) Placebo (Median, percentile 25-75) P-value
IL-6a 1(pg/ml) 28.70 (20.50–42.60) 21.50 (15.20–51.10) .194*
IL-6 2 22.70 (17.10–30.45) 25.50 (16.80–55.40) .396**
% Change −20.91 18.60  
TNF-αb 1(pg/ml) 4.00 (3.60–5.25) 4.30 (3.60–5.60) .218*
TNF-α 2 3.50 (3.15–4.97) 4.35 (3.15–4.97) .097**
% Change −12.50 1.16  
hs-CRP 1(mg/l) 2.95 (.92–7.30) 2.88 (1.31–15.40) .505*
hs-CRP 2 1.15 (.82–2.32) 1.29 (.82–2.90) .390**
% Change −61.02 −55.21  
  1. *P value is reported based on the Mann–Whitney U Test
  2. **P value is reported based on the Mann–Whitney U Test (for changes of values during the intervention period)
  3. aInterleukin-6
  4. bTumor necrosis factor-α