Table 4 Serum levels of proinflammatory cytokines in two groups of patients

From: The effect of n-3 polyunsaturated fatty acids on incidence and severity of oxaliplatin induced peripheral neuropathy: a randomized controlled trial

	n-3 PUFAs (Median, percentile 25–75)	Placebo (Median, percentile 25-75)	P-value
IL-6^a 1(pg/ml)	28.70 (20.50–42.60)	21.50 (15.20–51.10)	.194*
IL-6 2	22.70 (17.10–30.45)	25.50 (16.80–55.40)	.396**
% Change	−20.91	18.60
TNF-α^b 1(pg/ml)	4.00 (3.60–5.25)	4.30 (3.60–5.60)	.218*
TNF-α 2	3.50 (3.15–4.97)	4.35 (3.15–4.97)	.097**
% Change	−12.50	1.16
hs-CRP 1(mg/l)	2.95 (.92–7.30)	2.88 (1.31–15.40)	.505*
hs-CRP 2	1.15 (.82–2.32)	1.29 (.82–2.90)	.390**
% Change	−61.02	−55.21

*P value is reported based on the Mann–Whitney U Test
**P value is reported based on the Mann–Whitney U Test (for changes of values during the intervention period)
^aInterleukin-6
^bTumor necrosis factor-α

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