Table 2 Associations of IFITM1 expression in primary tumors with clinicopathological data
From: Expression of IFITM1 as a prognostic biomarker in resected gastric and esophageal adenocarcinoma
Factor | Entire cohort median (range) | p-value | Esophagus median (range) | p-value | GE junction median (range) | p-value | Stomach median (range) | p-value |
|---|---|---|---|---|---|---|---|---|
Age | ||||||||
≤ average >average | 1.75 (0.00-10.50) 2.00 (0.00-12.00) | 0.103 | 2.00 (0.00-10.50) 1.00 (0.00-7.50) | 0.363 | 2.50 (0.00-9.80) 2.50 (0.00-12.00) | 0.693 | 0.00 (0.00-9.00) 2.50 (0.00-12.00) | 0.001 |
Sex | ||||||||
Female Male | 2.50 (0.00-11.00) 1.00 (0.00-12.00) | 0.207 | 4.00 (1.00-6.50) 1.00 (0.00-10.50) | 0.080 | 2.50 (0.00-6.50) 2.00 (0.00-12.00) | 1.000 | 2.00 (0.00-11.00) 1.00 (0.00-12.00) | 0.588 |
T-stage | ||||||||
T1 T2 T3 T4 | 1.75 (0.00-10.00) 2.00 (0.00-12.00) 1.75 (0.00-12.00) 1.00 (0.00-12.00) | 0.805 | 2.00 (0.00-8.00) 2.25 (0.00-7.50) 1.25 (0.00-9.80) 0.50 (0.00-7.00) | 0.400 | 1.75 (0.00-3.50) 0.50 (0.00-4.00) 2.50 (0.00-12.00) 2.50 (2.00-8.00) | 0.669 | 1.00 (0.00-10.00) 3.00 (0.00-12.00) 1.25 (0.00-11.00) 1.00 (0.00-12.00) | 0.883 |
N-stage | ||||||||
N0 N1 N2 N3 | 2.00 (0.00-12.00) 2.00 (0.00-12.00) 1.00 (0.00-12.00) 1.75 (0.00-10.50) | 0.585 | 2.25 (0.00-8.00) 2.00 (0.00-6.50) 0.75 (0.00-9.80) 1.50 (0.00-10.50) | 0.471 | 2.50 (0.00-12.00) 3.00 (0.00-11.00) 1.25 (0.00-8.00) 2.75 (0.00-9.80) | 0.694 | 1.25 (0.00-12.00) 2.50 (0.00-12.00) 2.00 (0.00-12.00) 0.50 (0.00-6.00) | 0.504 |
M-stage | ||||||||
M0 M1 | 2.00 (0.00-12.00) 0.50 (0.00-6.50) | 0.033 | 1.75 (0.00-10.50) 1.25 (0.00-5.50) | 0.528 | 2.50 (0.00-12.00) 2.00 (0.00-6.50) | 0.693 | 2.00 (0.00-12.00) 0.00 (0.00-2.00) | 0.011 |
R-classification | ||||||||
R0 R1 R2 | 2.00 (0.00-12.00) 1.00 (0.00-9.80) 0.00 (0.00-10.00) | 0.055 | 2.00 (0.00-10.50) 1.00 (0.00-9.80) 0.00 (0.00-0.00 | 0.444 | 3.00 (0.00-12.00) 2.00 (0.00-7.00) 0.125 (0.00-0.30) | 0.252 | 2.00 (0.00-12.00) 0.50 (0.00-4.50) 0.25 (0.00-10.00) | 0.225 |
Differentiation grade | ||||||||
High Intermediate Low | 2.00 (0.00-3.00) 2.00 (0.00-12.00) 1.50 (0.00-12.00) | 0.759 | 2.00 (1.00-2.00) 2.00 (0.00-10.50) 1.00 (0.00-8.00) | 0.629 | 2.50 (2.50-2.50 1.50 (0.00-5.50) 2.50 (0.00-12.00) | 0.586 | 0.50 (0.00-3.00) 3.00 (0.00-12.00) 1.00 (0.00-12.00) | 0.324 |
Lauren classification | ||||||||
Intestinal Mixed Diffuse | 2.00 (0.00-12.00) 1.00 (0.00-6.50) 0.50 (0.00-12.00) | 0.150 | 1.75 (0.00-10.50) 1.875 (0.00-6.50) 0.00 (0.00-0.00) | 0.191 | 2.00 (0.00-12.00) 3.00 (0.00-3.00) 3.50 (0.00-12.00) | 0.565 | 3.00 (0.00-12.00) 0.25 (0.00-0.50) 0.38 (0.00-10.00) | 0.008 |
Intestinal metaplasia background | ||||||||
No Yes | 1.00 (0.00-12.00) 2.25 (0.00-12.00) | 0.083 | 1.00 (0.00-10.50) 2.00 (0.00-7.00) | 0.446 | 2.00 (0.00-12.00) 4.25 (0.00-12.00) | 0.090 | 0.75 (0.00-12.00) 1.75 (0.00-12.00) | 0.271 |
Location | ||||||||
Esophagus GE junction Stomach | 1.50 (0.00-10.50) 2.50 (0.00-12.00) 1.00 (0.00-12.00) | 0.829 |