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Fig. 2 | Biomarker Research

Fig. 2

From: Evaluation of Caspase-9b and PP2Acα2 as potential biomarkers for chronic lymphocytic leukemia

Fig. 2

Analysis of Caspase-9b and PP2Acα2 in healthy donors and CLL patients. a. Conventional PCR analysis of three healthy donors and three CLL patients for Caspase-9 and PP2Acα full length and spliced variants expression. b. Percentage of CLL patients that present normal, moderately dysregulated and highly dysregulated relative abundance of Caspase-9b and PP2Acα2. c. Real Time PCR analysis of healthy donors. Relative abundance values of spliced forms have been normalized with respect to full length forms, considered as 1. The limits for moderately dysregulated values are marked with a grey dotted line and the limits for highly dysregulated values with a black dotted line. d. Real Time PCR analysis of CLL patients. The same criteria as for Fig. 2c were applied for calculations and limits representation. Asterisk represents P < 0.005 (P = 0.0024), when compared with healthy donor

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