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Fig. 1 | Biomarker Research

Fig. 1

From: Treatment with rituximab and brentuximab vedotin in a patient of common variable immune deficiency-associated classic Hodgkin lymphoma

Fig. 1

Histology of the bone marrow biopsy at the diagnosis CVID-associated classic Hodgkin lymphoma. a Photomicrograph of the infiltrate in the marrow comprising very large Hodgkin and Reed-Sternberg (HRS) cells in a fibroinflammatory background (Hematoxylin and eosin stain, 1000X). b & c CD30 and CD20 immunohistochemistry is positive in HRS cells respectively (3′,3′-diaminobenzidine chromogen with hematoxylin counterstain, 1000X). d In situ hybridization for Epstein-Barr-virus-encoded RNA 1 (EBER 1) is positive in HRS cells (INFORM EBER probe and iVIEWTMblue detection, Ventana Medical Systems, Inc., Tuscon, AZ. 1000X)

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Biomarker Research

ISSN: 2050-7771

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