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Table 1 Patient characteristics

From: Ruxolitinib improves symptoms and quality of life in a patient with systemic mastocytosis

 

Baseline

Week 4

Week 8

Week 12

Week 16

Week 20

Week 24

Hemoglobin

12

11.7

11.3

10.5

10.9

11.4

11.6

Platelet count

188

246

277

297

314

296

250

WBC

6.3

6.8

6.9

7.3

7.4

8.0

8.3

Creatinine

0.85

0.88

0.89

0.92

1.02

1.16

1.03

ALT/AST

Normal

Normal

Normal

Normal

Normal

Normal

Normal

Amylase/Lipase

Normal

Normal

Normal

Normal

Normal

Normal

Normal

EKG

Normal

Normal

Normal

Normal

Normal

Normal

Normal

Weight (Kg)

77.9

78.4

80.5

83.7

85.2

85.6

84.6

Tryptase

10.2

NA

10.8

9.6

NA

9.5

9.1

Ruxolitinib dose

5 mg BID

10 mg BID

20 mg BID

15 mg BID

10 mg BID

10 mg BID

5 mg BID