A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers

Biomarker Research

Table 2 Characteristic of eligible studies included in meta-analysis of HIF1A 1790G/A polymorphism

Study	Year	Country	Ethnicity	Cancer	Case/Control	HWE
Clifford et al. [8]	2001	Caucasian	Caucasian	Renal cancer	48/144	0.866(Y)
Tanimoto et al. [9]	2003	Japan	Asian	Head neck squeamish cell carcinoma	55/110	0.655(Y)
Ollerenshaw et al. [10]	2004	Caucasian	Caucasian	Renal cancer	146/288	<0.001(N)
Fransen et al. [12]	2006	Sweden	Caucasian	Colorectal cancer	198/256	0.775(Y)
Orr-Urtreger et al. [30]	2007	Israel	Caucasian	Prostate cancer	200/300	0.954(Y)
Li et al. [14]	2007	USA	Mixed	Prostate cancer	1066/1264	0.810(Y)
Apaydin et al. [31]	2008	Turkey	Caucasian	Breast cancer	102/102	0.840(Y)
Kim et al. [16]	2008	Korea	Asian	Breast cancer	90/102	0.06(Y)
Muñoz et al. [32]	2009	Spain	Caucasian	Oral squamous cell carcinoma	64/139	0.693(Y)
Chen et al. [21]	2009	Taiwanese	Asian	Oral squamous cell carcinoma	174/347	0.701(Y)
Morris et al. [20]	2009	polish	Caucasian	Renal cancer	325/309	0.662(Y)
Li K et al. [33]	2009	Tibetan	Asian	Gastric cancer	87/106	0.764(Y)
Hsiao et al. [34]	2010	Taiwan	Asian	Hepatocellular carcinoma	102/347	0.701(Y)
Putra et al. [25]	2011	Japan	Asian	Lung cancer	83/110	0.655(Y)
Wang et al. [26]	2011	Japan	Asian	Pancreatic cancer	263/271	0.486(Y)
Kuo et al. [27]	2012	China	Asian	Lung cancer	285/300	0.154(Y)
Li et al. [28]	2012	China	Asian	Prostate cancer	662/716	0.554(Y)
Mera-Mene et al. [35]	2012	Spain	Caucasian	Lymph node metastasis	111/139	0.693(Y)
Qin et al. [36]	2012	Asian	Asian	Renal cancer	620/623	0.411(Y)

ISSN: 2050-7771