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Table 1 Characteristic of eligible studies included in meta-analysis of HIF1A 1772 C/T polymorphism

From: A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers

Study Year Country Ethnicity Cancer Case/Control HWE
Clifford et al. [8] 2001 UK Caucasian Renal cell carcinoma 35/143 0.018 (N)
Tanimoto et al. [9] 2003 Japanese Asian Head-neck cancer 55/110 0.545 (Y)
Ollerenshawa et al. [10] 2004 European Caucasian Renal cell carcinoma 160/162 <0.001 (N)
Chau et al. [11] 2005 USA Mixed Prostate cancer 196/196 <0.001 (N)
Franse et al. [12] 2006 Swedish Caucasian Colorectal cancer 198/258 0.916 (Y)
Konac et al. [13] 2007 Turkish Caucasian Cervical cancer 32/107 0.229 (Y)
Li et al. [14] 2007 American Mixed Prostate cancer 1041/1234 0.159 (Y)
Lee et al. [15] 2008 Korean Asian Breast cancer 1332/1369 0.250 (Y)
Kim et al. [16] 2008 Korean Asian Breast cancer 90/102 0.641 (Y)
Nadaoka et al.a [17] 2008 Japanese Asian Transitional cell carcinoma of bladder 219/461  
Jacobs et al. [18] 2008 American Mixed Prostate cancer 1420/1450 0.041 (N)
Foley et al. [19] 2009 Ireland Caucasian Prostate cancer 95/188 0.623 (Y)
Morris et al. [20] 2009 Polish Caucasian Renal cell carcinoma 332/313 0.083 (Y)
Chen et al. [21] 2009 Taiwanese Asian Oral squamous cell carcinoma (OSCC) 174/347 0.722 (Y)
Shieh et al. [22] 2010 Taiwan Asian Oral squamous cell carcinoma (OSCC) 305/96 0.710 (Y)
Knechtel et al.a [23] 2010 Austria Caucasian Colorectal cancer 368/2156  
Kang et al.a [24] 2011 Korean Asian Colorectal cancer 50/50  
Putra et al. [25] 2011 Japanese Asian Lung cancer 83/110 0.545 (Y)
Wang et al. [26] 2011 Chinese Asian Pancreatic cancer 263/271 0.352 (Y)
Kuo et al. [27] 2012 Taiwanese Asian Lung cancer 285/300 0.132 (Y)
Li et al. [28] 2012 China Asian Prostate cancer 662/716 0.267 (Y)
Fraga et al. [29] 2014 Portuguese Caucasian Prostate cancer 754/736 0.400 (Y)
  1. aFrequency of genotypes “CT + TT”. HWE Hardy-Weinberg Equilibrium