Table 2 Summary of reports of t(7;12) leukaemias with treatments and clinical outcome

[15]

DCLSG/POG

10

5

Treatment N/S

6 died of leukemia

1 died of leukemia and infection

1 died of infection

1 died of treatment related toxicity

1 alive, 22 months after BMT in CR1

[13]

CCG

2

2

1 relapsed in bone marrow with bilateral chloromas on the hips. Treated with radiation and BMT, but later died due to disease

1 relapsed twice, treated with BMT, alive after 2 years

[6]

DCOG

6

N/S

Treatment N/S

Median EFS: 9 months

3-year EFS: 0 %

3-year OS: 0 %

[19]

Japan

1

N/S

Alive after 5 years, treated with chemotherapy only

[16]

Korea

3

N/S

1 received cord blood transplantation at 11 months, relapsed 4 months later, then died at 16 months

1 died during induction chemotherapy from multiple organ failure

1 achieved remission, but relapsed at 10 months, and died at 16 months

[56]

COG

8

N/S

Treatment N/S

3-year EFS: 14 %

3-year OS: 28 %

2 of 7 evaluable patients are alive (1 after chemotherapy, 1 after BMT) (personal communication)