Paediatric acute myeloid leukaemia with the t(7;12)(q36;p13) rearrangement: a review of the biological and clinical management aspects

Table 1 Proportion of patients showing an HLXB9-ETV6 fusion transcript

No. of t(7;12) patients considered	No. of patients with HLXB9-ETV6 fusion transcript	Percentage of patients with HLXB9-ETV6 fusion transcript	Reference
2	2	100	[21]
7	4	57	[6]
2	1	50	[13]
1	1	100	[19]
7	4	57	[20]
6	6	100	[50]

Notes: The majority of patients considered in this table were reported as having the t(7;12) in the karyotype of their leukaemic cells. However, in 4 cases [13, 50, 56] the fusion transcript was described in patients with abnormalities of 7q and or 12p, implying that the t(7;12) might have been present, but underestimated in these cases

ISSN: 2050-7771