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Fig. 5 | Biomarker Research

Fig. 5

From: Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup

Fig. 5

Gene expression analysis of MB1 and MB2. Histograms show mRNA levels of the indicated genes in MB1 and MB2 compared to normal cerebella (average of n = 7) as control (CTR). In detail (a) GLI family members; (b) Sonic Hedgehog pathway (Hh) molecules and direct targets. (c) Cyclins. (d) Myc genes and Stemness molecules; (e) Differentiation molecules; (f) Epigenetic modifiers. The values of Relative Quantification are expressed in linear scale for panels (a), (c), (d), (e) and (f) and log scale for panel (b)

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