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Table 1 Clinicopathological features of breast cancer patients

From: Diagnostic and prognostic microRNAs in the serum of breast cancer patients measured by droplet digital PCR

Characteristics

Cohort A (n = 28)

Cohort B (n = 59)

Age

Mean age (SD)

65.3 (±14.4)

56.7 (±10.4)

Range

33–91

34–81

Menopausal status

Pre

3 (11 %)

14 (24 %)

Peri

7 (25 %)

1 (2 %)

Post

18 (64 %)

44 (75 %)

Histological subtype

Ductal

21 (75 %)

48 (81 %)

Lobular

4 (14 %)

4 (7 %)

Tubular

1 (4 %)

1 (2 %)

Other

2 (7 %)

6 (10 %)

Tumor size (pT)

pT1

21 (75 %)

28 (47 %)

pT2

7 (25 %)

27 (46 %)

pT3

0

4 (7 %)

Lymph node involvement (pN)

pN0

21 (75 %)

35 (59 %)

pN1

6 (21 %)

16 (27 %)

pN2

0

6 (10 %)

pN3

1 (4 %)

1 (2 %)

pNx

0

1 (2 %)

Metastasis (cM)a

M0

28 (100 %)

57 (97 %)

M1

0

2 (3 %)

Stage

I

16 (57 %)

24 (41 %)

II

11 (39 %)

24 (41 %)

III

1 (4 %)

9 (15 %)

IV

0

2 (3 %)

Grade

I

5 (18 %)

11 (19 %)

II

18 (64 %)

14 (24 %)

III

5 (18 %)

34 (58 %)

Estrogen receptor

Positive

26 (93 %)

41 (69 %)

Negative

2 (7 %)

16 (27 %)

Missing

0

2 (3 %)

Progesterone receptor

Positive

19 (68 %)

35 (59 %)

Negative

9 (21 %)

22 (37 %)

Missing

0

2 (3 %)

HER2/neu receptor

Positive

3 (11 %)

11 (19 %)

Negative

25 (89 %)

44 (75 %)

Uncertain

0

1 (2 %)

Missing

0

3 (5 %)

Triple negative

ER-/PR-/HER2-

1 (4 %)

9 (15 %)

  1. a cM Clinical evidence of metastasis
  2. HER2/neu human epidermal growth factor receptor 2, ER Estrogen receptor, PR Progesterone receptor