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Table 1 Median signature scores for each cancer type

From: Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs

Cancer

Median NtAI

Median LST

Median HRD-LOH

Average ranking

Receives first line platinum*

OV

24

20

15

1

Yes

LUSC

20

13

17

2

Yes

BLCA

16

11

9

3

Yes

HNSC

15

9

12

3

Yes

LUAD

15

10

11

3

Yes

BRCA

12

8

8

6

No

SKCM

9

6

7

7

Some

STAD

10

7

5

7

Yes

COAD

8

5

5

9

Yes

GBM

4

3

4

10

No

PRAD

4

6

2

11

No

KIRC

4

3

3

12

No

UCEC

3

2

2

13

No$

LAML

1

0

0

14

No

THCA

0

0

0

15

No$

  1. *Based on treatment information available from Cancer Research UK, which can be found via http://www.cancerresearchuk.org/about-cancer/type/ $Does not receive chemotherapy as first line, but may receive platinum-based chemotherapy for high stage or recurrent disease.