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Table 4 The clonal components of bone marrow samples taken from an ALL patient upon the initial diagnosis and post chemotherapy

From: Fluorescence in situ hybridization (FISH): an increasingly demanded tool for biomarker research and personalized medicine

Clone

Fusion

TEL

AML1

PAX5

P16

IKZF1

Initial diagnosis

1

1

2

2

2

2

1

1

3

2

2

2

1

1

3

2

1

2

Post chemotherapy

1

1

2

1

0

1

1

1

3

2

2

1

1

1

3

2

1

1

  1. Note: the numbers in FISH probe columns (Fusion, TEL, AML1, PAX5, p16 and IKZF1) indicate copy numbers of each gene (or gene fusion) within a single nucleus of the cancer clone.