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Table 4 The clonal components of bone marrow samples taken from an ALL patient upon the initial diagnosis and post chemotherapy

From: Fluorescence in situ hybridization (FISH): an increasingly demanded tool for biomarker research and personalized medicine

Clone Fusion TEL AML1 PAX5 P16 IKZF1
Initial diagnosis 1 1 2 2 2 2
1 1 3 2 2 2
1 1 3 2 1 2
Post chemotherapy 1 1 2 1 0 1
1 1 3 2 2 1
1 1 3 2 1 1
  1. Note: the numbers in FISH probe columns (Fusion, TEL, AML1, PAX5, p16 and IKZF1) indicate copy numbers of each gene (or gene fusion) within a single nucleus of the cancer clone.