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Table 4 Characteristics of patients and tissue subgroups stratified by HR and HER2 status

From: Vav2 protein overexpression marks and may predict the aggressive subtype of ductal carcinoma in situ

Tissue subgroups No. of samples (%) Patient age (years)
Mean (Median) Range
DCIS 64 (100%) 55.9 (57) 29-80
DCIS (ER+)a 38 (59.4%) 53.9 (54) 29-80
DCIS (HER2+)b 15 (23.4%) 55.9 (57) 35-69
DCIS (TN)c 11 (17.2%) 62.5 (64) 55-74
IDC 76 (100%) 56.1 (56) 28-88
IDC (ER+)a 38 (50.0%) 57.8 (56) 29-88
IDC (HER2+)b 14 (18.4%) 53.4 (53) 32-88
IDC (TN )c 24 (31.6%) 54.9 (58) 28-77
  1. aER -positive subgroups include ER+/PR+/-/HER2 – tumors; bHER2–positive subgroups include ER+/-/PR+/-/HER2+ tumors; c TN subgroups include ER-/PR-/HER2-.