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Table 4 Characteristics of patients and tissue subgroups stratified by HR and HER2 status

From: Vav2 protein overexpression marks and may predict the aggressive subtype of ductal carcinoma in situ

Tissue subgroups

No. of samples (%)

Patient age (years)

Mean (Median)

Range

DCIS

64 (100%)

55.9 (57)

29-80

DCIS (ER+)a

38 (59.4%)

53.9 (54)

29-80

DCIS (HER2+)b

15 (23.4%)

55.9 (57)

35-69

DCIS (TN)c

11 (17.2%)

62.5 (64)

55-74

IDC

76 (100%)

56.1 (56)

28-88

IDC (ER+)a

38 (50.0%)

57.8 (56)

29-88

IDC (HER2+)b

14 (18.4%)

53.4 (53)

32-88

IDC (TN )c

24 (31.6%)

54.9 (58)

28-77

  1. aER -positive subgroups include ER+/PR+/-/HER2 – tumors; bHER2–positive subgroups include ER+/-/PR+/-/HER2+ tumors; c TN subgroups include ER-/PR-/HER2-.