Box plots for unaggregated measurements of IGF-IR, Rap1, and Vav2 in three major histological groups of tissue: normal mammary epithelium, CIS and IBC. n, number of samples per group. +, mean value. Horizontal line, median. Boxes, 25th and 75th percentile. Whiskers, 75th +1.5 x IQR and 25th -1.5 x IQR. Dots, group outliers. Y axis, protein levels in relative units.