Table 1 IDH1 and IDH2 mutations and SNP 105C > T in 189 AML patients
Gene | Nucleotide change | Amino acid change | Number of patients |
|---|---|---|---|
IDH1 | CGT > TGT | R132C | 7 |
IDH1 | CGT > CAT | R132H | 6 |
IDH1 | CGT > GGT | R132G | 1 |
IDH1 | CGT > CTT | R132L | 1 |
IDH2 | CGG > CAG | R140Q | 20 |
IDH2 | CGG > GGG | R140G | 1 |
IDH2 | AGG > AAG | R172K | 5 |
IDH1 | GGC > GGT | G105G | 20 |