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Table 4 Dose reductions and discontinuations

From: Tolerability to romidepsin in patients with relapsed/refractory T-cell lymphoma

Characteristic

PTCL (N = 131)

CTCL (N = 102)

Dose reduction due to adverse events, n (%)

14 (11)

14 (14)

Dose interruptions due to adverse events, n (%)

61 (47)

35 (34)

Discontinuation, n (%)

  

 Progressive disease

78 (60)

22 (22)

 Adverse event

22 (17)

24 (24)

 Adverse event related to romidepsin treatment

11 (8)

17 (17)

 Othera

7 (5)

26 (26)

  1. CTCL, cutaneous T-cell lymphoma; PTCL, peripheral T-cell lymphoma.
  2. aMost often refers to withdrawal of consent.