Predictive value of tumor recurrence using urinary vascular endothelial factor levels in patients receiving radiation therapy for Glioblastoma Multiforme (GBM)

Table 3 Univariate and multivariate logistic regression analysis of patient characteristics and urinary VEGF for progression/death status at 1 year

	Univariate		Multivariate
Variable	p-value	OR Ϯ (95% CI)	p-value	ORϮ (95% CI)
(Bolded value has unfavorable outcome)
Assigned treatment (Arm 2 vs. Arm1)	0.76	0.87 (0.36, 2.13)	0.76	0.86 (0.32, 2.28)
Methylation status (unmethylated vs. methylated)	0.25	1.72 (0.68, 4.34)	0.18	2.04 (0.73, 5.75)
RPA (IV vs. III)	0.62	1.26 (0.51, 3.14)	0.99	0.99 (0.31,3.12)
RPA (V vs. III)	0.17	2.50 (0.67, 9.31)	0.73	1.30 (0.29, 5.90)
Baseline Normalized VEGF (continuous)	0.34	1.001(0.998,1.004)	0.45	1.001 (0.998,1.005)
Normalized VEGF change from End of RT to 1 month post RT (continuous)	0.50	1.000 (0.999,1.001)	0.31	0.999 (0.998,1.001)

Ϯ Odds ratio: the OR of 1 indicates no difference, and > 1 indicates higher failure rate with increasing values.

ISSN: 2050-7771