| RTOG 0611 patients with VEGF (n = 128) | RTOG 0525 patients not used in the analysis (n = 997) |
---|---|---|
Age | Â | Â |
<50 | 39 (30.5%) | 232 (23.3%) |
≥50 | 89 (69.5%) | 765 (76.7%) |
 | Chi-square p-value = 0.07 |  |
Gender | Â | Â |
Female | 72 (56.3%) | 570 (57.2%) |
Male | 56 (43.8%) | 427 (42.8%) |
 | Chi-square p-value = 0.84 |  |
KPS | Â | Â |
60-80 | 45 (35.2%) | 383 (38.4%) |
90-100 | 83 (64.8%) | 614 (61.6%) |
 | Chi –square p-value = 0.47 |  |
Surgery | Â | Â |
Biopsy | 3 (2.3%) | 47 (4.7%) |
Partial resection | 44 (34.4%) | 459 (46.0%) |
Total resection | 81 (63.3%) | 491 (49.2%) |
 | Chi-square p-value = 0.01 |  |
Neurologic function | Â | Â |
No symptoms | 55 (43.0%) | 309 (31.0%) |
Minor symptoms | 48 (37.5%) | 468 (46.9%) |
Moderate symptoms | 24 (18.8%) | 215 (21.6%) |
Severe symptoms | 1 (0.8%) | 5 (0.5%) |
 | Chi-square p-value = 0.02 |  |
RPA class | Â | Â |
III | 30 (23.4%) | 175 (17.6%) |
IV | 74 (57.8%) | 602 (60.4%) |
V | 24 (18.8%) | 220 (22.1%) |
 | Chi-square p-value = 0.24 |  |
MGMT status | Â | Â |
Methylated | 31 (25.0%) | 269 (27.0%) |
Unmethylated | 66 (53.2%) | 527 (52.9%) |
Unknown (indeterminate, invalid)/not done | 27 (21.8%) | 201 (20.2%) |
 | Chi-square p-value = 0.86 |  |
Treatment arms | Â | Â |
Not randomized | 28 (21.9%) | 264 (26.5%) |
Arm 1 | 58 (45.3%) | 353 (35.4%) |
Arm 2 | 42 (32.8%) | 380 (38.1%) |
 | Chi-square p-value = 0.09 |  |