Whole gene expression profile in blood reveals multiple pathways deregulation in R6/2 mouse model

Biomarker Research

Table 2 Selected genes investigated by RT-qPCR

Gene symbol	ENTREZ ID	GENE NAME	Affy Id	R6/2 vs WT FC	R6/2 vs WT p
Tpm2	22004	tropomyosin 2, beta	1425028_a_at	-1.8	0.016
Slc8a1	20541	solute carrier family 8 (sodium/calcium exchanger), member 1	1437675_at	-1.36	0.047
C3	12266	complement component 3	1423954_at	4.51	0.000
Serping1	12258	serine (or cysteine) peptidase inhibitor, clade G, member 1	1416625_at	2.6	0.009
Slc27a2	26458	solute carrier family 27 (fatty acid transporter), member 2	1416316_at	3.27	0.000
Fabp1	14080	fatty acid binding protein 1, liver	1448764_a_at	20.35	0.018

Table reports name, symbol and entrez ID (obtained from NCBI database) of each gene. Corresponding Affy id together with relative Fold Change (FC) and p-value (p) obtained by microarray statistical analysis (Section Methods) are also showed.

ISSN: 2050-7771